Kraepelin died while working on the ninth edition of Psychiatrie with Johannes Lange —who finished it and brought it to publication in Morel, however, did not conduct any long-term or quantitative research on the course and outcome of dementia praecox Kraepelin would be the first in history to do that so this prognosis was based on speculation.
It is impossible to discern whether the condition briefly described by Morel was equivalent to the disorder later called dementia praecox by Pick and Kraepelin. Based on his theory that dementia praecox is the product of autointoxication emanating from the sex glands, Kraepelin experimented, without success, with injections of thyroid, gonad and other glandular extracts.
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The fourth edition of his textbook, Psychiatrie , published in , two years after his arrival at Heidelberg, contained some impressions of the patterns Kraepelin had begun to find in his index cards. Prognosis course and outcome began to feature alongside signs and symptoms in the description of syndromes, and he added a class of psychotic disorders designated "psychic degenerative processes", three of which were borrowed from Kahlbaum and Hecker: dementia paranoides a degenerative type of Kahlbaum's paranoia, with sudden onset , catatonia per Kahlbaum, and dementia praecox , Hecker's hebephrenia of Schizophrenia was mentioned as an alternate term for dementia praecox in the Statistical Manual.