Sex linked sex influenced and sex limited in Baltimore

Full size image. The model also predicts that autistic females will have, in general, lower IQs than autistic males A schematic illustration is given in Figure 2. Accordingly, a genetic mechanism is thought to be responsible for the strong familiality.

The genetic locus is silenced when it is transmitted by a mother and is switched on when transmitted by a father. World Health OrganizationGeneva. Note that the mean ability in the domain illustrated in Figure 3 i is lower in both groups of Turner's females than normal females 3 ii.

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Uniparental disomy of the entire X chromosome in a female with Duchenne muscular dystrophy. The table is not all-inclusive, but it provides enough data to show the greater severity of these diseases in males, and to illustrate why some, but not all, females with the same X-linked deleterious allele are protected from its effects.

A nongenetic explanation for male vulnerability, such as exposure to prenatal androgens, is unlikely for a variety of reasons. Shin J. Sex differences in the prevalence of autism have been described in both singleton sex linked sex influenced and sex limited in Baltimore multiplex families 1 — 4.

Ann Hum Genet 61 : —

  • A phenotypic characteristic or trait such as male pattern baldness that is expressed differently in males and females, usually because its expression depends on androgens or oestrogens, and that is controlled by a single gene that is dominant in males but recessive in females, so that, for example, men who inherit the gene from either parent lose hair as they age, whereas women do so only if they inherit it from both parents and are thus homozygotes.
  • Each individual has a pair of sex chromosomes ; one member of the pair is inherited from each parent.
  • Occurring or appearing only in one sex. Used of a genetic character or phenotype.

Lord C, Rutter M, LeCouteur A Autism Diagnostic Interview revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Johns Hopkins University Press, Baltimore.

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Sex linked sex influenced and sex limited in Baltimore

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